Abstract No. 159 Combination Therapy Transarterial Ethanol Lipiodol Embolization and Percutaneous Microwave Ablation of Unresectable Intermediate to Large Sized Hepatocellular Carcinoma

To examine the outcomes of patients treated with combination therapy transarterial ethanol and Lipiodol embolization percutaneous microwave ablation unresectable intermediate to large-sized hepatocellular carcinoma. This an IRB-approved retrospective study. From January 2018- October 2018, 20 (16M, 4 F, ages 51-85, Mean age 67) carcinoma (HCC) solitary lesions less than 6 cm (3.1–6.0 cm, median 4.1 cm) without extrahepatic disease were trans-arterial followed by image-guided ablation. Embolization was performed selectively utilizing emulsion 1:2 concentration Lipiodol. Image-guided 1 week post embolization. Univariable analysis overall survival (OS) progression-free (PFS) through Kaplan-Meier curves log-rank tests. Technical success TAELE MW 100%. Median OS not reached as 16 still living at greater 36 months. 1,2,3 year is 100%, 90% 80% respectively. PFS 12 demonstrated complete response no progression. 80%, 70%, 60% There a statistically significant increase in for < 5 (P< 0.0001). Hepatitis B associated lower 0.05). Location lesion presence cirrhosis did significantly impact or OS. Combination effective method treating large HCC. most when size cm.